
After missing out on European football with a seventh-placed finish in the Premier League last season, United entered Wednesday’s draw alongside the other 12 top-flight sides not involved in UEFA Champions League or Europa League action this term.
Under the leadership of new manager Louis van Gaal, United will travel to stadiummk in the week commencing August 25 to take on Karl Robinson’s men, who finished 10th in the third tier in 2013-14.
Four-time winners of this competition, United reached the semi-finals last season, before being knocked out on penalties by Sunderland.
Gus Poyet’s side went on to lose the final 3-1 to Manchester City at Wembley, and will begin their campaign at Birmingham City this time out.
Of the Premier League’s three newly promoted sides, Burnley and Leicester City have been handed home ties against Sheffield Wednesday and Shrewsbury Town respectively, while QPR will visit Burton Albion.
West Ham and Sheffield United will face each other for the first time since the Carlos Tevez controversy that surrounded the latter’s relegation from the top flight in 2007.
Other ties involving Premier League clubs will see Aston Villa host Leyton Orient, Crystal Palace visit Walsall and West Brom welcome League Two Oxford United.
Newcastle United will make the long trip to Kent to take on Gillingham, while Stoke City face Portsmouth, Swansea City host Rotherham United and Southampton venture to the New Den to take on Millwall.
Burton Albion v QPRPort Vale v Cardiff CityMiddlesbrough v Preston North EndStoke City v PortsmouthHuddersfield Town v Nottingham ForestSwansea City v Rotherham UnitedWatford v Doncaster RoversMillwall v SouthamptonBournemouth v Northampton TownBrentford v FulhamWest Brom v Oxford UnitedScunthorpe United v ReadingDerby County v Charlton AthleticWest Ham v Sheffield UnitedSwindon Town v Brighton and Hove AlbionLeicester City v Shrewsbury TownCrewe Alexandra v Bolton WanderersBirmingham City v SunderlandGillingham v Newcastle UnitedNorwich City v Crawley TownBradford City v Leeds UnitedAston Villa v Leyton OrientBurnley v Sheffield WednesdayWalsall v Crystal PalaceMK Dons v Manchester United